Werlhof's Disease, also known as idiopathic thrombocytopenic purpura (ITP), is a rare autoimmune disorder that causes low platelet count and abnormal bleeding. There are some synonyms for Werlhof's Disease, which are used interchangeably in medical literature. These include primary immune thrombocytopenia, autoimmune thrombocytopenic purpura, immune-mediated thrombocytopenia, and acquired thrombocytopenic purpura. Immune thrombocytopenic purpura (ITP) is a more commonly used term to describe Werlhof's disease. While the disease is uncommon, it can cause serious complications, such as excessive bleeding and bruising, and requires careful medical management. Early diagnosis and treatment can help reduce the risk of complications and improve outcomes for affected individuals.