Botherers refer to people who annoy or pester others. There are many synonyms that can be used to describe someone who is a botherer, such as pest, annoyance, irritant, agitator, tormentor, harasser, and heckler. These terms can be used to describe different types of botherers, such as someone who constantly interrupts or someone who persistently criticizes. Other synonyms include nuisance, troublemaker, meddler, busybody, and disturber. Each of these terms conveys the idea of someone who is bothersome in one way or another, and they can be used in different contexts to describe different types of annoying people.